Chemists have found potential drugs and other really useful compounds in some truly bizarre places in nature, and who would have ever thought that blood from the Komodo dragon could have a secret inside of it that could possibly save your life. But it doesn’t end there, so we’re taking a closer look at other wild places in nature that we’ve found fantastic drugs!
Al Segars, Ph.D.
Jacqueline Fries, Ph.D.
John Yates, Ph.D.
Darcy Gentleman, Ph.D.
Roberto Daglio – Con Todo Meu Amor
Smidi – Cadillac Candy
Special Thanks to Schoolyard Films for giving us the awesome Horseshoe Crab Blood milking footage. See their in depth video on horseshoe crabs here:
Antibacterial resistance – https://www.cdc.gov/getsmart/community/about/antibiotic-resistance-faqs.html
Antimicrobials in Komodo Dragon blood – http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.6b00857
VK25 inspires the DRGN-1 peptide – https://www.nature.com/articles/s41522-017-0017-2
MRSA is getting crazy – https://thefern.org/ag_insider/pig-related-infections-spread-denmark-may-u-s/
Dendrilla Membrosa – http://pubs.acs.org/doi/abs/10.1021/np50123a020
Darwinolide Story – https://phys.org/news/2016-06-antarctic-sponge-deadly-mrsa-infection.html
Horseshoe crabs “over 300 million years old” – https://www.nwf.org/Wildlife/Wildlife-Library/Invertebrates/Horseshoe-Crab.aspx
3-15% die, based on interviews with biologists –
Evolutionary info on horseshoe crabs –
The original 1956 paper by Frederick Bang that got everything going –
How Blue Blood coagulates around endotoxins –
Hemocyanin – http://www.jbc.org/content/276/19/15563.full